Using mathematical modeling, women in Malawi who were determined to be recently infected with HIV were almost three times as likely to see in-utero HIV transmission than those who had been infected for longer periods of time. Transmission rates were 17.8% for recently infected women and 6.7% for those less recently infected. This was determined to be independent of viral load at delivery.
Citation:
Taha TE, James MM, Hoover DR, Sun J, Laeyendecker O, Mullis CE, Kumwenda JJ, Lingappa JR, Auyert B, Morrison CS, Mofensen LM, Taylor A, Fowler MG, Kumenda NI, Eshleman SH. Association of recent HIV infection and in-utero HIV-1 transmission. AIDS. 2011 Jul;25(11):1357-64.
Original Article (subscription may be required)
Abstract
Citation:
Taha TE, James MM, Hoover DR, Sun J, Laeyendecker O, Mullis CE, Kumwenda JJ, Lingappa JR, Auyert B, Morrison CS, Mofensen LM, Taylor A, Fowler MG, Kumenda NI, Eshleman SH. Association of recent HIV infection and in-utero HIV-1 transmission. AIDS. 2011 Jul;25(11):1357-64.
Original Article (subscription may be required)
Abstract